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Causes of Osteolytic and Osteoblastic metastases

*Causes of Osteolytic metastasis :
- Kidney (expansile) and Thyroid : Expansile lytic osseous metastasis are characteristic of Renal cell carcinoma (kidney) and Thyroid .
- Lung
- Gastrointestinal tract (GIT)
- Breast (occasionally)
- Less commonly melanoma, carcinoma of bronchus and pheochromocytoma may also present with Expansile lytic lesions.

*Causes of Osteoblastic metastasis :
- Prostate
- Breast (may be mixed)
- Seminoma
- Carcinoid 
- Neurogenic tumors
- Uterus 
- Ovary


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