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Pathology Mcq's

-Answers will be posted later-


1)Which of the following is not included in the major Jones criteria for diagnosing rheumatic heart disease ?
(a) Pancarditis. (b) Chorea. (c)Arthritis. (d)Elevated ESR.

(2)The lipoprotein most often associated with heart disease is:
(a)Very low density lipoprotein. (b)Chylomicrons. ©Low density lipoproteins. (d)High density lipoproteins.


(3)The most important cause of acute right ventricular failure is:
(a)Pulmonary stenosis. (b)Tricuspid stenosis. ©Mitral stenosis.
(d)Massive pulmonary embolism.

(4)Which of the following factors does not predispose to bacterial endocarditis?
(a)Catheterization. (b)Intravenous injections. ©Hypertension.
(d)Tooth extraction.

(5)Left ventricular hypertrophy is not seen in:
(a)Aortic regurgitation. (b)Aortic stenosis. ©Mitral regurgitation.
(d) Mitral stenosis.


(6)The earliest lesion of atherosclerosis is:
(a)Fatty streak. (b)Fibrous plaque. ©Medial thinning. (d)Platelet aggregation.

(7)Major risk factors associated with development of coronary and generalized atherosclerosis include all of the following except:
(a)Cigarette smoking. (b)Elevated high density lipoprotein(HDL) levels. ©Diabetes mellitus. (d)Hypercholesterolaemia.

(8)Which one of the following blood groups has an association with gastric carcinoma?
(a) O. (b) A. ©B. (d)AB.


(9)Peptic ulcer has an association with blood group:
(a) O. (b) A. ©B. (d)AB.


(10)The organism associated with peptic uleer is :
(a)E.coli. (b)Mycobacterium tuberculosis. ©Helicobacter pylori. (d)Klebsiella.


(11)The commonest cause of oesophagitis is:
(a)Alcoholism. (b)Reflux oesophagitis. ©Spices. (d)Smoking.



(12)‘Skip lesions’ in intestine is the term applied to lesions of:
(a)Chronic ulcerative colitis. (b)Crohn’s disease . ©Typhoid ulcer. (d)Tuberculosis.


(13)The commonest site of gastric ulcer is :
(a)Greater curvature. (b)Lesser curvature. ©Gastro-oesophageal junction. (d)Duodenum.


(14)The commonest site of gastric cancer is :
(a)Pylorus and antrum. (b)Cardia. ©Body. (d) Fundus.


(15)Taenia coli are seen in the :
(a)Stomach . (b)Duodenum. ©lleum. (d)Colon.

(16)‘Caput medusae’ is associated with :
(a)Pancreatic carcinoma. (b)Cirrhosis of the liver. ©Polyposis coli.
(d)Hepatocellular carcinoma.

(17)The Dane Particle is:
(a) Hepatitis A virus (HAV). (b) Hepatitis B virus (HBV).
© Hepatitis C virus (HCV). (d) Hepatitis E virus (HEV).


(18)The most common organism associated with osteomyelitis is:
(a)Staphylococcus aureus. (b)E.coli. ©Pseudomonas. (d)Klebsiella.
(19)The part of a long bone initially involved in haematogenous osteomyelitis is the :
(a)Metaphyseal region. (b)Diaphysis. ©Epiphysis. (d) Area around the entrance of the nutrient artery.


(20)Ovarian homologue of seminoma of testis is :
(a) Embryonal carcinoma. (b)Dysgerminoma. © Yolk sac tumour. (d)Choriocarcinoma.


(21)Paget’s disease of the nipple is associated with:
(a)Ductal carinoma of the breast. (b)Lobular carcinoma of the breast.
©Medullary carcinoma of the breast. (d)Melanoma.
(22)The most common type of mammary malignancy is :
(a)Cystosarcoma phyllodes. (b)Lobular carcinoma. © Infiltrating ductal carcinoma. (d)Intraductal papillary carcinoma.

(23)A major risk factor for squamous carcinoma of the cervix is now considered to be:
(a) Early sexual activity. (b)Multiple sexual partners. ©Human papillomavirus. (d) Frequency of coitus.


(24)In the list below, the ovarian tumour with the highest degree of bilateral involvement is:
(a)Serous cystadenoma. (b)Mucinous cystadenoma. ©Mucinous cystadenocarcinoma. (d) Serous cystadenocarcinoma.


(25) The condition most likely to predispose an elderly male to development of penile squamous intraepithelial neoplasm is :
(a)Phimosis. (b)Herpes simplex virus infection. ©Lichen simplex chronicus.
(d)Epispadius.


(26)‘Single file infiltration’ of cells is seen in which type of breast cancer?
(a)Tubular carcinoma. (b)Invasive lobular carcinoma. ©Infiltrating ductal carcinoma. (d)Medullary carcinoma.


(27)Which one of the following provides an example of concomitant hyperplasia and hypertrophy?
(a)Uterine growth during pregnancy. (b)Left ventricular cardiac hypertrophy.
©Enlargement of skeletal muscle in atheletes. (d)Breast enlargement at puberty.

(28)A woman from which of the following countries has the greatest risk for development of breast carcinoma?
(a)Japan. (b)India. ©Zimbabwe. (d)United States.


(29)Early detection of squamous cell carcinoma of the cervix with Pap smear screening is important because:
(a)The survival from in situ forms is virtually 100%. (b)They usually progress rapidly . ©There is a tendency to transform into sarcomas. (d)They are difficult to detect posmenopausally.

(30)A 25 year old female has a firm , rubbery ,mobile mass palpable in the left breast.This is probably a (an):
(a)Focus of fat necrosis. (b)Fibroadenoma. ©Intraductal papilloma.
(d)Infiltrating ductal carcinoma.
(31)Which of the following hormones is not secreted by the anterior pituitary?
(a)Antidiuretic hormone(ADH). (b)Follicle stimulating hormone(FSH).
©Luteinizing hormone (LH). (d)Growth hormone.

(32)A 30 year old woman with amenorrhoea-galactorrhoea, headaches and visual field defects probably has which of the following ?
(a) Cushing’s syndrome. (b)Paget’s disease of bone. ©Prolactinoma.
(d) Neurofibroma.

(33)Which of the following physical or laboratory findings is most typically associated with Graves’ disease (diffuse toxic goiter)?
(a)Myxedema. (b)Anti-TSH receptor antibody. ©Decreased iodine uptake. (d)Papillary carcinoma.

(34)A 29 year old primigravida has a placenta previa with extensive blood loss and shock during delivery. Following recovery , She is most likely to have which of the following problems?
(a)Cushing’s syndrome. (b)Lack of menstrual cycles. ©Galactorrhoea.
(d)Diabetes insipidus.

(35)Psammoma bodies may be seen in the following tumours except:
(a)Follicular carcinoma of the thyroid . (b)Meningioma.
©Papillary carcinoma of the thyroid. (d)Serous cystadenocarcinoma of the ovary.

(36)Well differentiated follicular carcinoma of the thyroid is differentiated from follicular adenoma of the thyroid by which of the following features?
(a) Hurthle cell change. (b)Small follicles lined by tall cuboidal to columnar cells. ©Increased mitosis. (d)Vascular invasion.

(37) True statements regarding minimal change disease include all of the following except:
(a)It occurs most often in children. (b)The glomerulus appears normal by light microscopy. © Nephrotic syndrome frequently occurs . (d) Serum complement is often decreased .

(38)Clinically ,crescentic glomerulonephritis characteristically manifests as :
(a)Rapidly progressive disease. (b)Indolent clinical course with gradual progression to chronic renal failure. ©Nephrotic syndrome . (d)Asymptomatic haematuria.


(39)The clinical complex of nephritic syndrome is usually characterized by all of the following findings except:
(a)Acute onset. (b)Haematuria with red blood cell casts . ©Some degree of oliguria. (d) Proteinuria of >3.5gm/day.

(40)The commonest renal calculi associated with proteus infections are :
(a)Cystine stone. (b)Triple phosphate stone. ©Uric acid stone.
(d)Calcium oxalate stone.

(41)The following statements are true of childhood polycystic kidney disease except:
(a)Autosomal dominant. (b)Manifests at birth. ©Cysts in kindney and liver. (d)Association with congenital hepatic fibrosis.

(42)Tte term ‘thyroidisation’ is applied to which organ?
(a)Heart. (b)Kidney. ©Liver. (d) Ovary.

(43)Xanthogranulomatous pyelonephritis shows the following features except:
(a)Accumulation of fatty macrophages . (b)Yellow nodules in kidney. ©Association with tuberculosis. (d)Presence of giant cells.


(44)Causes of ‘flea-bitten’kidney include the following except:
(a)Acute poststreptococcal glomerulonephritis. (b)Rapidly progressive glomerulonephritis . ©Haemolytic uraemic syndrome. (d)Benign nephrosclerosis.


(45)Which of the following cells of the central nervous system arise from bone marrow (monocytes)?
(a)Neurons. (b)Astrocytes. © Ependymal cells. (d)Microglia.


(46)A 32 year old female living in Idaho came to her physician because of acute onset of left arm weakness. Several years before, she had loss of vision in her left eye which lasted only a week .She probably has :
(a)A low grade astrocytoma. (b)Multiple sclerosis. ©Embolic stroke from endocarditis. (d)Ruptured intracranial aneurysm.

(47)A 66 year old male is finding that he has more difficulty moving about .He is annoyed by a tremor in his hand , but the tremor goes away when he performs routine tasks using his hands . He has not suffered loss of mental ability. He probably has:
(a)Alzheimer’s disease. (b) Parkinson’s disease. © Niemann-Pick disease. (d)Tuberous sclerosis.

(48)The family of a 55 year old male is finding that he can no longer care for himself and he cannot even remember where the bathroom in the house is .This man has :
(a)Depigmentation of the substantia nigra .(b) Many senile plaques in the cerebrum. ©A granuloma near the brainstem. (d)Large,vacuolated neurons in the cerebrum.

(49)The most common route of spread of infection to the brain is :
(a)Via venous route . (b)Via arterial route . ©Via lymphatics . (d)Along nerves.

(50)Glucose content of CSF is unaltered in the following type of meningitis:
(a)Acute pyogenic meningitis. (b)Acute viral meningitis. ©Cryptococcal meningitis.
(d)Tubercuous meningitis.

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